A REVIEW OF CAN YOU CRUSH PHENOBARBITAL

On initiation or discontinuation of guselkumab in patients who will be acquiring concomitant CYP450 substrates, specifically those with a slender therapeutic index, consider monitoring for therapeutic effect.Monitor Carefully (1)phenobarbital will decrease the level or effect of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism.